GENOME PROJECT

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Science Special Online Collection: The Macaque Genome

The rhesus macaque genome sequence was published in the April 13, 2007 issue of Science and is already providing valuable information to a number of research areas. For our own work, we have used the sequence to design probes for our macaque oligonucleotide microarray. The sequence also allows for the generation of databases of predicted macaque proteins, a requirement for mass spectrometry based proteomics approaches that require such a database for peptide and protein identification. In addition, the ability to cross-annotate rhesus and human genes is of considerable value for performing functional analyses on gene expression and protein abundance data.

Please visit the Rhesus Genome Project at the Baylor College of Medicine for additional information on the macaque genome and for access to data downloads.